acute pain
Conditions
Interventions
Control group:Meperidine hydrochloride
Sponsors
The Third People's Hospital of Chengdu
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: (1) Age =18 years old, both sexes; (2) Emergency patients requiring opioid analgesics; (3) Moderate or severe patients with numerical rating scale (NRS) =4; (4) Informed consent was obtained from patients or their families.
Exclusion criteria
Exclusion criteria: (1) Pregnant or lactating women; (2) A known history of allergy to any study drug; (3) A history of long-term opioid use or opioid addiction; (4) The presence of diseases that may affect opioid analgesic metabolism; (5) Systolic blood pressure < 90 mmHg, heart rate < 50 beats/min, blood oxygen saturation < 95%; (6) Alcohol or other drug poisoning; (7) Symptoms of respiratory depression, acute or severe bronchial asthma; (8) Patients with or at risk of progression to gastrointestinal obstruction, especially paralytic ileus; (9) Hearing or vision loss, or any other condition that may significantly interfere with study data collection; (10) Patients with mental and neurological diseases, cognitive and consciousness disorders and unable to express correctly, and sedated patients; (11) Use of opioids within the past 24 hours; (12) Drugs with investigational drug interactions; (13) Have participated in this study or in any other study simultaneously.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| pain relief rate;Target analgesia target time;adverse reaction; | — |
Secondary
| Measure | Time frame |
|---|---|
| location of pain;percentage of target analgesia scores achieved at each time point;total dose of analgesia drugs;Rescue analgesics, total dose;Length of emergency department stay;changes of vital signs; | — |
Countries
China
Contacts
Public ContactXiang Tao
The Third People's Hospital of Chengdu
Outcome results
None listed