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Quantitative evaluation of left ventricular function in patients with snake bite using two-dimensional speckle tracking technology

Quantitative evaluation of left ventricular function in patients with snake bite using two-dimensional speckle tracking technology

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400089862
Enrollment
Unknown
Registered
2024-09-18
Start date
2023-03-03
Completion date
Unknown
Last updated
2024-09-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

snakebite

Interventions

Experimental group:Snake bite
Control group:Health control

Sponsors

Chongqing Fourth People's Hospital (Chongqing Emergency Medical Center)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
14 Years to 75 Years

Inclusion criteria

Inclusion criteria: Experimental group inclusion criteria: ? Patients with clinically confirmed venomous snake bites; ? Between 14-75 years old; ? The time from bite to hospital admission is not more than 24 hours; (4) Hospital stay more than 5 days; ? The two-dimensional echocardiographic image quality was good, and the left interior membrane margin could be clearly displayed. Control group inclusion criteria: ? Between 14-75 years old; ? The image quality of two-dimensional echocardiography is good, and the left interior membrane margin can be clearly displayed.

Exclusion criteria

Exclusion criteria: Exclusion criteria for experimental group: ? Pregnancy; ? Other drug treatment before admission: such as antivenom, drugs that damage or protect the heart muscle; ? There are basic diseases that cause heart function injury: such as systemic immune diseases, diabetes, uremia, hyperthyroidism, coronary heart disease, etc.; ? Various factors that affect image quality, such as obesity and emphysema. Control group exclusion criteria: ? Did not take heart-damaging drugs treatment: such as antivenom, heart-damaging drugs ? There are basic diseases that cause heart function injury: such as systemic immune diseases, diabetes, uremia, hyperthyroidism, coronary heart disease, etc ? Various factors that affect image quality, such as obesity or emphysema

Design outcomes

Primary

MeasureTime frame
Left ventricular long axis strain under endocardium;Left ventricular long axis strain beneath the cardiac membrane;Epicardial left ventricular long axis strain;cardiac troponin I,cTnI;a-hydroxybutyrate dehydrogenase,a-HBDH;left atrial reservoir strain,LASr ;left atrial conduit strain,LAScd ;left atrial contraction strains,LASct ;Right ventricular strain of the free wall,RVFWS ;Right ventricular global longitudinal strain,RVGLS ;

Secondary

MeasureTime frame
White blood cell count;Hypersensitive C-reactive protein;Creatinekinase,CK;Creatine Kinase isozyme MB,CK-MB;lactic dehydrogenase,LDH;

Countries

China

Contacts

Public Contactchenjing

Chongqing Fourth People's Hospital (Chongqing Emergency Medical Center)

790915538@qq.com+86 159 2288 4645

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026