Helicobacter pylori infection
Conditions
Interventions
14d-VA:Amoxicillin-containing 14-day dual therapy
14d-VM:Minocycline-containing 14-day dual therapy
14d-VBAM:14-day regimen of bismuth quadruple therapy with minocycline
7d-VBAM:7-day regimen of bismuth quadruple therapy with minocycline
Sponsors
West China Hospital of Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: (1) Age>= 18 years and = 6 or 14C>= 150); (3) No previous Helicobacter pylori eradication therapy; (4) Patients were informed and agreed to participate in this trial.
Exclusion criteria
Exclusion criteria: (1) Pregnant or breastfeeding women, or patients who plan to have children during the study; (2) Patients who have taken acid inhibitors, H2-receptor blockers, bismuth or antibiotics within 4 weeks before treatment; (3) Patients with serious problems in other organs (such as liver disease, cardiovascular disease, lung disease, kidney disease, metabolic disease, malignant tumors, neuropsychiatric diseases, etc.); (4) Patients who are allergic to any of the drugs used; (5) Patients who are unable to express their complaints correctly, such as those with mental illness, severe neurosis and inability to cooperate; (6) Any other health condition assessed by the doctor as not suitable for inclusion in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The eradication rate of Helicobacter pylori; | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse reactions; | — |
Countries
China
Contacts
Public ContactLi Hong
West China Hospital of Sichuan University
Outcome results
None listed