Neuropathic pain after spinal cord injury
Conditions
Interventions
At-level SCI NP group:Transcranial magnetic stimulation
At-level SCI NP sham group:Sham stimulation
Below-level SCI NP group:Transcranial magnetic stimulation
Below-level SCI NP sham group:Sham stimulation
Sponsors
The Second Affiliated Hospital of Kunming Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Age 18-75 years old; (2) The pain lasts for at least 1 month; (3) Persistent pain (at least 4 days per week),NRS screening pain score of at least 4; (4) DN4 score =4 points; (5) Stable medication for at least 1 month prior to inclusion.
Exclusion criteria
Exclusion criteria: (1) Have a history of cognitive impairment or mental illness; (2) Treatment is not available; (3) Patients with severe pain from other sources, such as musculoskeletal pain; (4) Other types of NP not associated with spinal cord injury, such as postherpes zoster NP, diabetic neuropathy NP; (5) Patients with At-level SCI NP and Below-level SCI NP simultaneously; (6) Head trauma, alcohol or drug abuse; (7) pregnancy or epilepsy; (8) Contraindications of TMS, such as metal implants in the head, cardiac pacemakers, etc.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Patient’s Global Impression of Change;Self-rating anxiety scale;Self-rating Depression Scale;Pittsburgh Sleep Quality Index;Electromyography;motor evoked potential;Somatosensory evoked potential;functional near - infrared spectroscopy ;Inflammatory factor detection; | — |
Primary
| Measure | Time frame |
|---|---|
| Numerical rating scale; | — |
Countries
China
Contacts
Public ContactLi Yongmei
The Second Affiliated Hospital of Kunming Medical University
Outcome results
None listed