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Effect of sleep-weak timing on postoperative delirium in older adults undergoing non-cardiac surgery: A prospective cohort study

Effect of sleep-weak timing on postoperative delirium in older adults undergoing non-cardiac surgery: A prospective cohort study

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400089831
Enrollment
Unknown
Registered
2024-09-18
Start date
2024-10-01
Completion date
Unknown
Last updated
2024-09-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative delirium

Interventions

Early chronotypes group:None
Late chronotypes group:None

Sponsors

The First Hospital of China Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 100 Years

Inclusion criteria

Inclusion criteria: For patients =65 years of age, ASA grade I to III, who plan to undergo elective general anesthesia for non-cardiac surgery, the expected operation time is =30 minutes, and the expected postoperative hospital stay is at least 3 days

Exclusion criteria

Exclusion criteria: (1) Previous history of dementia, delirium or neurological and psychiatric diseases caused by various causes; (2) Postoperative admission to ICU; (3) Had night work before or one week after surgery, and had received general anesthesia in the month before inclusion; (4) long-term use of melatonin related drugs; (5) Suffering from sleep apnea syndrome; (6) Unwilling or unable to cooperate with investigators due to communication difficulties, severe hearing or visual impairment;

Design outcomes

Primary

MeasureTime frame
Postoperative delirium;

Secondary

MeasureTime frame
Cognitive function at 30 days after surgery;Objective sleep quality;Postoperative chronic pain;Subjective sleep quality;Postoperative acute pain;C-reactive protein;Cholinesterase;Albumin;

Countries

China

Contacts

Public ContactBo Fang

Department of Anesthesiology, The First Hospital of China Medical University

bfang@cmu.edu.cn+86 135 9165 2713

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026