Skip to content

Efficacy and safety evaluation of tranexamic acid essence in improving chloasma and postinflammatory hyperpigmentation

Efficacy and safety evaluation of tranexamic acid essence in improving chloasma and postinflammatory hyperpigmentation

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400089829
Enrollment
Unknown
Registered
2024-09-18
Start date
2024-09-23
Completion date
Unknown
Last updated
2024-09-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chloasma and postinflammatory hyperpigmentation

Interventions

Experimental group (Melasma/ Postinflammatory hyperpigmentation):Using test products

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1) 18 years old and above, female; 2) There is pigmentation that meets the clinical diagnostic criteria for melasma or is diagnosed as postinflammatory hyperpigmentation; 3) No recent family planning; 4) Persisting in completing the entire course of treatment; 5) High compliance; 6) During the treatment and follow-up period, no other diseases were treated simultaneously.

Exclusion criteria

Exclusion criteria: 1) Within 6 months have been oral or topical retinoic acid, hormones, tranexamic acid, and other drugs; 2) Suffering from other types of skin diseases; 3) Pregnant women or severe cardiovascular, liver, and kidney diseases; 4) In the past 3 months, laser, intense pulsed light, and chemical peeling agent systems have been used to treat chloasma or postinflammatory hyperpigmentation.

Design outcomes

Primary

MeasureTime frame
Redness;skin color;

Secondary

MeasureTime frame
Loss of moisture through the epidermis;Skin stratum corneum moisture content;Security assessment;

Countries

China

Contacts

Public ContactWang Xi

West China Hospital, Sichuan University

xierwang@126.com+86 28 8542 2075

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026