Respiratory depression
Conditions
Interventions
Group Remimazolam:Induction and maintenance of anesthesia with remimazolam
Group Propofol :Induction and maintenance of anesthesia with propofol
Sponsors
Central Hospital of Dalian University of Technology
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Female patients undergoing elective breast surgery under general anesthesia without intubation; ASA Class ?-?; Patients who have signed the informed consent and subject declaration.
Exclusion criteria
Exclusion criteria: BMI>30kg/m2 ; History of obstructive sleep apnea hypopnea syndrome; Patients or their families refuse to participate in the experiment; Patients with a history of alcohol abuse or allergies to general anesthesia drugs, kidney or liver diseases, breastfeeding or recent respiratory infections; Patients with significant hearing or visual impairment, inability to communicate and cooperate (coma, dementia, language impairment); Poor compliance of patients or family members; Patients who have changed their original treatment plan.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Respiratory depression; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood pressure;Heart rate;Etco2;SpO2;Aldrete Scoring System;OAA/S Scoring System;Visual Analogue Scale;Postoperative nausea and vomiting, PONV;Postoperative recovery quality;Postoperative delirium, POD;Injection pain; | — |
Countries
China
Contacts
Public ContactCongjie Bi
Central Hospital of Dalian University of Technology
Outcome results
None listed