low rectal cancer
Conditions
Interventions
experimental group:After intra-abdominal anastomosis is completed, a drainage tube is placed through the anus
control group:After the completion of intra-abdominal anastomosis, perform prophylactic fistulization on the terminal ileum
Sponsors
West China Hospital of Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) Age range: 18-80 years old 2) Diagnosed with primary rectal cancer 3) The distance between the tumor and the anal margin is 7-3cm 4) Anesthesia ASA classification is I-III 5) Proposed laparoscopic low anterior resection for rectal cancer 6) Preoperative ECOG physical status score: 0 or 1 7) The main organ functions are normal and meet the following requirements: A. Blood routine examination (no blood transfusion in the past 14 days): HB = 90g/L; ANC =1.5×109/L; PLT =80×109/L B. Blood biochemistry test: BIL<1.5 times the upper limit of normal (ULN); ALT and AST<2.5 × ULN; Crea = 1 × ULN.
Exclusion criteria
Exclusion criteria: 1) Patients undergoing emergency surgery 2) Contraindications for laparoscopic surgery: Patients who are deemed unsuitable for laparoscopic surgery based on preoperative evaluation. 3) Received neoadjuvant radiotherapy before surgery 4) Patients with combined inflammatory bowel disease, FAP, recurrent rectal cancer or multiple primary cancers 5) The proposed surgical approach is non laparoscopic low anterior resection for rectal cancer, such as intersphincteric resection (ISR) for rectal cancer and abdominal perineal resection (APR) for rectal cancer. 6) History of unstable angina, myocardial infarction, cerebral infarction, or cerebral hemorrhage in the past 6 months. 7) History of continuous systemic corticosteroid treatment within the past month. 8) Pulmonary function test FEV1 is less than 50% of the expected value. 9) Pregnant or lactating women. 10 suffer from severe mental illness. 11) Refuse to sign the informed consent form for the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of anastomotic fistula within 30 days after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| The incidence of severe surgical related complications within 30 days after surgery; | — |
Countries
China
Contacts
Public ContactYang Lie
West China Hospital of Sichuan University
Outcome results
None listed