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Effects of preoperative Dexmedidine Hydrochloride Nasal Spray for induction of anesthesia and recovery in preschool children.

Effects of preoperative Dexmedidine Hydrochloride Nasal Spray for induction of anesthesia and recovery in preschool children.

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400089818
Enrollment
Unknown
Registered
2024-09-18
Start date
2024-09-18
Completion date
Unknown
Last updated
2024-09-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

preoperative anxiety

Interventions

Group M:Dexmedetomidine hydrochloride nasal spray (10.7kg weight <19.4kg, 30µg
19.4kg weight 28.0kg, 50 µ g) ,Spitnose one left and one right nostrils
Control group (Group D):0.9% saline,Spitnose one left and right nostrils

Sponsors

Department of Anesthesiology, Meishan People's Hospital.
Lead Sponsor

Eligibility

Sex/Gender
All
Age
2 Years to 6 Years

Inclusion criteria

Inclusion criteria: 1. Children from 2 to 6 years of age; 2. Surgery under general anesthesia; 3. ASA grade?-?; 4. Operation duration less than 2 hours; 5 the child had no abnormal growth and development; 6 no abnormal electrocardiogram, chest radiograph, routine blood, electrolytes and liver and kidney function tests.

Exclusion criteria

Exclusion criteria: 1. Children with fever, cold, cough and other symptoms or asthma or other respiratory diseases; 2. Children with mental retardation, mental retardation, epilepsy and other neurological diseases or mental disorders; 3. 4. Children with arrhythmia and other important organ dysfunction; 5. Children who have had craniocerebral surgery or craniocerebral trauma; 6. Disabled children.

Design outcomes

Primary

MeasureTime frame
odifieed Yale preoperative anxiety scale-short form,m-YPAS;induction compliance checklist,ICC;Emergence Delirium ;

Secondary

MeasureTime frame
Aaking time and PACU residence time;Use of analgesics in PACU;Adverse Reaction ; the does of additional anesthetics during the operation;

Countries

China

Contacts

Public ContactHongxia He

Meishan People's Hospital

18160179605@163.com+86 181 6017 9605

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026