Chronic Obstructive Pulmonary Disease
Conditions
Interventions
COPD+IPA group:no intervention
control group:no intervention
Sponsors
The Chongqing Songshan General Hospital
Eligibility
Sex/Gender
All
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Age: =40 years; 2.Diagnosed with COPD according to the 2020 GOLD Strategy and the 2021 Chinese COPD Diagnosis and Treatment Guidelines; 3.First onset of the disease, including both outpatient and inpatient infections; 4.Confirmed (EORTC/MSG 2019 criteria) or clinically suspected (Bulpa 2007 criteria) or clinically highly probable diagnosis (Bulpa 2007 criteria) of invasive pulmonary aspergillosis.
Exclusion criteria
Exclusion criteria: Patients with HIV, malignant tumors, post-major organ transplantation, post-stem cell transplantation, or severe hereditary immunodeficiency disease (CD4 count less than 200/µL).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum GM test;Sputum GM test;Bronchoalveolar lavage fluid GM test;Fungal cultures of sputum or BALF;Aspergillus IGG antibody detection;Aspergillus PCR detection;mNGS; | — |
Countries
CHINA
Contacts
Public ContactQiao Zhang
The Chongqing Songshan General Hospital
Outcome results
None listed