Ventilator-induced diaphragmatic dysfunction
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: ? Patients who need to establish invasive mechanical ventilation for more than 48 hours due to various reasons; ? Over 18 years old; ? The skin in the sternocleidomastoid region was not damaged. ? Stable vital signs; ? The guardian signs the informed consent
Exclusion criteria
Exclusion criteria: ? There are contraindiations of percutaneous diaphragmatic nerve stimulation (such as temporary or permanent pacemaker installation, severe arrhythmia, hemodynamic instability, untreated severe pneumothorax, pleural thickening and adhesion, history of neck surgery, etc.); The presence of neuromuscular lesions (such as myasthenia gravis) or known anatomical abnormalities of the diaphragm; ? There are factors that affect ultrasonic determination, such as a large number of pleural effusion, intraperitoneal high pressure, abdominal infection, pregnancy, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of ventilator-associated diaphragmatic dysfunction;Diaphragmatic thickening score;partial pressure of carbon dioxide pco2; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood gas oxygen partial pressure;Mechanical ventilation time;Median length of ICU stay; | — |
Countries
China
Contacts
The First Hospital of Jiaxing