early-stage knee osteoarthritis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: ?In line with the diagnostic criteria of early-stage knee osteoarthritis; ?Aged between 40 and 70, no gender limitation; ?VAS score between 30mm and 70mm; ?Voluntarily participate in this study and sign an informed consent form complete all treatment courses and follow ups of the project;
Exclusion criteria
Exclusion criteria: ?Complicated with serious heart / liver / kidney / blood and other internal diseases; ?Complicated with joint inflammatory diseases such as rheumatoid arthritis / gouty arthritis / ankylosing spondylitis and other diseases affecting lower extremity function; ?Pregnant patients; ?Those who have received knee related surgery within six months; ?Patients who are allergic to Celebrex or have obvious contraindications; ?Patients who have received knee joint medication injections within the past 3 months; ?Patients who have undergone regular lower limb muscle training for more than one month prior to participating in the experiment;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Western Ontario and McMaster Universities Osteoarthritis Index WOMAC; | — |
Secondary
| Measure | Time frame |
|---|---|
| Health Survey Short Form 36-item, SF-36;Visual Analogue Scale, VAS;Strength of knee;Knee range of motions; | — |
Countries
China
Contacts
Shuguang Hospital Affiliated to Shanghai University of Chinese Medicine