acute herpes zoster neuralgia
Conditions
Interventions
dexmedetomidine combined with hydromorphone patient-controlled intravenous analgesia group (experimental group):dexmedetomidine combined with hydromorphone patient-controlled intravenous analgesia
Opioid group (control group):Oral Tramadol
Sponsors
Leshan Chinese Medicine Hospital
Eligibility
Sex/Gender
All
Age
50 Years to 85 Years
Inclusion criteria
Inclusion criteria: ?medical history of no more than one month, NRS score =4; ? age =50 years; ? received antiviral therapy (acyclovir 800 mg 5 times/day or valacyclovir 1000 mg 5 times/day for 7 days); ?no previous history of hypotension or bradycardia; ? voluntarily signed the informed consent form, and were able to cooperate with the completion of the followup assessment and operation of the PCA pump.
Exclusion criteria
Exclusion criteria: ?Patients with allergy to opioids and experimental drugs; ?Patients with combined severe cardiac, pulmonary, and renal insufficiency; ?Patients with infections, mental anomalies, and other conditions that prevent them from cooperating with the treatment; ?Patients with paralytic intestinal obstruction; and ?Patients who are older and have difficulty communicating with the patient for evaluation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Numeric rating scales; | — |
Secondary
| Measure | Time frame |
|---|---|
| The incidence of zoster-related pain;Pittsburgh sleep quality index;CD4+ CD8+ CD4+/CD8+;Daily dosage; | — |
Countries
China
Contacts
Public ContactYu qingwen
Leshan Chinese Medicine Hospital
Outcome results
None listed