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Effect of different neoadjuvant treatment regimens on intraoperative hypotension and postoperative related complications in patients with esophageal cancer: a real-world study

Effect of different neoadjuvant treatment regimens on intraoperative hypotension and postoperative related complications in patients with esophageal cancer: a real-world study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400089724
Enrollment
Unknown
Registered
2024-09-13
Start date
2024-03-01
Completion date
Unknown
Last updated
2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

esophageal tumor

Interventions

non-immunotherapy group:None

Sponsors

Jiangsu Cancer Hospital(The affliated Cancer Hospital of Nanjing Medical University)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 1. ASA grade II to III; 2. initial gastroscopic pathology with a definitive diagnosis of esophageal squamous carcinoma; 3. receiving preoperative neoadjuvant therapy; 4. patients who underwent surgery for esophageal cancer from January 2020 to December 2023 at our institution.

Exclusion criteria

Exclusion criteria: 1. Combination of severe cardiac, pulmonary, hepatic, renal, cerebral and immune system diseases (e.g. NYHA cardiac function = grade III, FEV1%pred <50%, Child Pugh classification = grade C, blood creatinine =177umol/L, etc.); 2. combined history of other malignant tumors; 3. patients with distant metastases.

Design outcomes

Primary

MeasureTime frame
Incidence of intraoperative hypotension;Intraoperative vasoactive drug utilization;

Secondary

MeasureTime frame
Number of intraoperative hypotensive events;Intraoperative vasoactive drug dosage and type;Cardiac enzyme profile;Incidence of intraoperative hypoxemia;Incidence of pulmonary complications ;Postoperative hospitalization time;chest tube drainage time;relative counts of lymphoid subgroups;indicators of liver and kidney function (alanine aminotransferase, glutamine aminotransferase, bilirubin, albumin, creatinine, urea nitrogen, uric acid);calcitoninogen;C-reactive protein;troponin T ;N-terminal B-type natriuretic peptidogen;

Countries

CHINA

Contacts

Public ContactLiu Hui

Jiangsu Cancer Hospital(The affliated Cancer Hospital of Nanjing Medical University)

huilium@163.com+86 138 1304 3213

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026