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Effect of tACS on motor recovery after stroke: a randomized controlled trial

Effect of tACS on motor recovery after stroke: a randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400089716
Enrollment
Unknown
Registered
2024-09-13
Start date
2024-09-15
Completion date
Unknown
Last updated
2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke

Interventions

tACS:On the basis of conventional rehabilitation treatment, apply tACS(77.5Hz,15mA) over frontal cortex and two mastoids for 10 times
sham stimulation:On the basis of conventional rehabilitation treatment, apply sham-tACS for 10 times

Sponsors

Ruijin Hospital, Shanghai Jiaotong University School Of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. In line with the diagnostic criteria for stroke developed by the Fourth National Conference on Cerebrovascular Diseases, confirmed by head CT or MRI; 2. The first cerebral infarction or cerebral hemorrhage and the course of disease ranging from 3 to 12months; 3. Stable vital signs; conscious, and cooperative with examination and treatment; 4. Aging from 18 to 80 years old; 5. Hemiplegic limbs and hand Brunnstrom staging 3 to 5; 6. Informed consent to the study and sign the relevant documents.

Exclusion criteria

Exclusion criteria: 1.Heart, lung, liver, kidney and other important organ function decline or failure and malignant tumors; 2.There are serious cognitive and communication disorders and can not be combined with treatment; 3.Stroke caused by non-cerebrovascular disease; 4.Have a history of epilepsy in 3 months or use epileptic drugs; 5.Wearing a pacemaker, intracranial implanted metal; 6.Skull defects.

Design outcomes

Primary

MeasureTime frame
FMA-UL (Fugl-meyer assessment of upper limb);

Secondary

MeasureTime frame
FMA-LL(Fugl-meyer assessment of lower limb);Action Research Arm Test;grip;modified Ashworth scale;Hamilton depression scale-17;Pittsburgh Sleep Quality Index;Montreal Cognitive Assessment Scale;visual analogue scale;Modified Barthel Index;

Countries

China

Contacts

Public ContactQing Xie

Ruijin Hospital, Shanghai Jiaotong University School Of Medicin

ruijin_xq@163.com+86 188 4645 5231

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026