Sleep disturbance after knee and hip arthroplasty
Conditions
Interventions
Dexametholidine group: 10 min before the induction, patients were injected intravenously with dexmetomidine 0.5-1.0 µ g / (kg ·h) for 30 min. After that, the pump was maintained at 0.2 ~ 0.4 µ g / (kg
Stellate ganglion block group:Before anesthesia induction, 7ml 0.5% ropivacaine hydrochloride was injected into the right stellate ganglion block under the guidance of ultrasound. The puncture was suc
Stellate ganglion block combined with dexmetomidine group:15 min before anesthesia induction, 7ml 0.5% ropivacaine hydrochloride was injected into the right stellate ganglion block under the guidance
Control group:10 min before anesthesia induction, the patients were injected with the same volume of normal saline as the dexmetomidine group until the induction was completed.
Sponsors
Affiliated Hospital of Xuzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Unilateral total knee arthroplasty or total hip arthroplasty (including osteoarthritis, osteonecrosis of the femoral head, fracture, etc.) under elective general anesthesia; 2.Age = 18 years old; 3.BMI 18.5-30 kg/m^2;4.ASA grade ?-?
Exclusion criteria
Exclusion criteria: People who are allergic to experimental drugs; 2. Preoperative Athens Insomnia scale (AIS)>6; 3. Have rheumatic immune system diseases such as rheumatoid arthritis and systemic lupus erythematosus; 4. Have neuromuscular or psychiatric disorders; 5.Complication with severe cardiovascular, cerebrovascular, and pulmonary diseases or severe liver and kidney dysfunction before surgery; 6. Unable to understand or cooperate in completing relevant scales; 7. Coagulation dysfunction, local skin infection; 8. Refuse to sign an informed consent form or participate in other clinical trials at the same time; 9. The mode of anesthesia was changed to intraspinal anesthesia or other non-general anesthesia; 10. Serious accidents occurred during the operation (massive hemorrhage, cardiac arrest, etc.); 11. Postoperative infection or other complications or other operations; 12. The patient asked to withdraw from the trial or was unable to complete the follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of postoperative sleep disturbance; | — |
Secondary
| Measure | Time frame |
|---|---|
| Athens Insomnia scale;Numerical Rating Scale;Hospital Anxiety and Depression Scale;Heart rate;Mean arterial pressure;Opioid dosage; | — |
Countries
China
Contacts
Public ContactShen Wen
Affiliated Hospital of Xuzhou Medical University
Outcome results
None listed