Diffuse large B cell lymphoma
Conditions
Interventions
Control Group:Subjects were followed up regularly every 3 months for a total of 12 months as prescribed by the physician.
Test Group: The above Chinese medicinal herbs were all provided by the Chinese herbal pharmacy of Yueyang Hospital of Integrative Medicine, Shanghai University of Traditional Chinese Medicine, and dec
the frequency of the follow-up observation time was consistent with that of the control group.
Sponsors
Shanghai University of Traditional Chinese Medicine, China
Eligibility
Sex/Gender
All
Age
29 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patients with diffuse large B-cell lymphoma definitively diagnosed on the basis of tissue biopsy, clinical symptoms, and laboratory tests and clinically assessed to be in complete remission (CR) or indeterminate complete remission (CRu) after completion of the R-CHOP/CHOP chemotherapy regimen; 2. 18 years = age = 75 years, gender is not limited; 3. TCM disease identification consistent with phlegm-toxicity disease, meeting the diagnostic criteria of Zhengxu phlegm coagulation syndrome; 4. Kanofskky score (KPS) =70 points (can take care of themselves, but cannot live and work normally); 5. Understanding, agreeing to participate in this study and signing the informed consent.
Exclusion criteria
Exclusion criteria: 1. Severe vital organ insufficiency (NYHA cardiac function class 3-4; pulmonary hypoplasia class 3-4; hepatic function Child-Pugh class C; renal function CKD class 3-5); 2. Previous diagnosis of a malignancy other than non-Hodgkin's lymphoma; 3. Pregnant or lactating patients; 4 .Active or uncontrolled serious infection (= CTCAE grade 2 infection); 5. Consciousness and mental disorders and lack of independent judgment; 6. Those who have participated or are participating in other clinical trials within 2 weeks prior to enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Relapse; | — |
Secondary
| Measure | Time frame |
|---|---|
| 1-year progression-free survival (PFS) rate;TCM Symptom Score;Karnofsky score;Tumor load indicators (LDH, ß2-MG, ferritin);Cytokines (IL-2, IL-6, IFN-?, TNF-a); | — |
Countries
China
Contacts
Public ContactLi Jiekai; Zhou Yongming
Yueyang Hospital of Integrative Medicine, Shanghai University of Traditional Chinese Medicine, China
Outcome results
None listed