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Application of remifentanil combined with neuromuscular blockers in pediatric endotracheal intubation

Application of remifentanil combined with neuromuscular blockers in pediatric endotracheal intubation

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400089691
Enrollment
Unknown
Registered
2024-09-13
Start date
2024-03-18
Completion date
Unknown
Last updated
2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The children’s intubation under general anesthesia

Interventions

experimental group:During routine induction of anesthesia with long-acting opioid, desponxant, and propofol, a small dose of remifentanil
control group:During routine induction of anesthesia with long-acting opioid, desponxant, and propofol

Sponsors

Beijing Children's Hospital, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 12 Years

Inclusion criteria

Inclusion criteria: 1.General anesthesia with intubation is required for elective surgery; 2. Aged 12 years old or less; 3. ASA grade?to ?; 4. Preoperative fasting > 6 h, no breast milk / formula > 4 h, no clear drinks > 2 h.

Exclusion criteria

Exclusion criteria: 1. There is severe gastroesophageal reflux, tracheoesophageal fistula, and esophageal hiatal hernia 2. Difficult tracheal intubation is expected 3. Severe cardiac insufficiency 4. Liver and kidney dysfunction 5. Combined with congenital heart disease

Design outcomes

Primary

MeasureTime frame
No major complications (including cough, motility, hemodynamic changes more than +/- 30%) were successful first intubation;

Secondary

MeasureTime frame
Time from complete induction of anesthesia to successful endotracheal intubation;Success rate of first tracheal intubation;Number of intubations;Pulse oxygen saturation, heart rate and mean arterial pressure immediately before and after successful endotracheal intubation and 5min after induction;

Countries

China

Contacts

Public ContactWang Fang

Beijing Children's Hospital, Capital Medical University

wangfang@bch.com.cn+86 189 1061 9300

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026