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A prospective, open, single-arm, single-center study to evaluate the diagnostic staging value of 18F-FAPI-FUSCC PET/CT for medullary thyroid carcinoma

A prospective, open, single-arm, single-center study to evaluate the diagnostic staging value of 18F-FAPI-FUSCC PET/CT for medullary thyroid carcinoma

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400089672
Enrollment
Unknown
Registered
2024-09-12
Start date
2024-09-13
Completion date
Unknown
Last updated
2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Medullary thyroid carcinoma

Interventions

Sponsors

Fudan University Shanghai Cancer Center
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Voluntarily sign an informed consent form. 2. Age = 18 years old. 3. MTC patients highly suspected or confirmed through pathological or routine imaging examinations, with CT levels>150 pg/mL and CEA greater than the upper limit of the reference value. 4. According to the doctor's assessment, the estimated survival period is 3 months. 5. Agree to implement strict contraception for at least 28 days after PET/CT examination. 6. Willing and able to follow the research protocol.

Exclusion criteria

Exclusion criteria: 1. Patients diagnosed with other malignant tumors in the past year. 2. Patients diagnosed with other pathological types of thyroid cancer during follow-up. 3. Patients undergoing any anti-tumor treatment between two PET/CT examinations. 4. Pregnant or lactating women. 5. Unable to cooperate with lying on the PET/CT scanning bed during the scanning period or intolerant to PET examination. 6. Patients who have received or are currently receiving radiotherapy, chemotherapy, immunotherapy, or molecular targeted therapy. 7. Have participated in other intervention clinical trials within the first month prior to screening. 8. Patients who have been lost to follow-up. 9. According to the researcher's evaluation, the subjects may have other circumstances that may affect the study or may not be suitable for participation in the study.

Design outcomes

Primary

MeasureTime frame
SUVmax (Standardized Uptake Value max);

Countries

China

Contacts

Public ContactShaoli Song

Fudan University Shanghai Cancer Center

shaoli_song@fudan.edu.cn+86 138 1660 8573

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026