Periodontal Disease
Conditions
Interventions
Control group:None
Periodontal treatment group:Administer Dydrogesterone tablets (10 mg) orally starting from the 15th day of the menstrual cycle, twice daily, for 10 days each month.
Sponsors
Shengli Oilfield Central Hospital
Eligibility
Sex/Gender
Female
Age
40 Years to 45 Years
Inclusion criteria
Inclusion criteria: Inclusion Criteria: 1. Diagnosis of moderate to severe periodontitis according to the "2017 World Workshop on the Classification of Periodontal and Peri-implant Diseases and Conditions" (Tonetti et al., 2018); 2. A clear diagnosis in the progesterone group, requiring treatment with oral progesterone for at least 3 months; 3. A minimum of 20 natural teeth (excluding third molars) in the oral cavity; 4. No other diseases requiring concurrent medication.
Exclusion criteria
Exclusion criteria: Exclusion Criteria: 1. History of periodontal treatment within the past year; 2. History of using antibiotics and/or immunosuppressants within the past six months; 3. History of systemic diseases such as diabetes, hypertension, osteoporosis, rheumatoid arthritis, joint diseases, bone metabolic diseases, and/or malignant tumors; 4. Patients with oral mucosal diseases; 5. Patients with orthodontic appliances in the mouth.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The probing depth (PPD); | — |
Secondary
| Measure | Time frame |
|---|---|
| bleeding on probing (BOP) ;sulcus bleeding index (SBI);plaque index,PLI; | — |
Countries
China
Contacts
Public ContactYing Man
Shengli Oilfield Central Hospital
Outcome results
None listed