Postoperative analgesia after laparoscopic total hysterectomy
Conditions
Interventions
Group nalbuphine:Nalbuphine 0.2 mg/kg given before induction of anesthesia
Group sufentanil:Sufentanil 0.2 ug/kg given before induction of anesthesia
Sponsors
The Second Affiliated Hospital of Shandong First Medical University
Eligibility
Sex/Gender
Female
Age
40 Years to 49 Years
Inclusion criteria
Inclusion criteria: ?American Society of Anesthesiologists (ASA) class ?~?; ?Surgical indications for laparoscopic total hysterectomy; ?Age: 40~49 years old; ?Estimated duration of surgery <3h; ?Patient's pain sensitivity score 4~6; ?Voluntary signing of informed consent.
Exclusion criteria
Exclusion criteria: ? emergency surgery; ? combined with serious cardiac, hepatic and renal dysfunction; ? preoperative application of other analgesic and sedative, antiemetic, anti-inflammatory drugs; ? combined with a history of smoking, alcohol consumption; ? combined with clinical factors affecting nociception, such as diabetes mellitus; ? severe OSAHS and obese patients (BMI = 30kg/m2); ? combined with psychiatric system diseases
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| postoperative visceral pain;postoperative body pain; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of postoperative adverse reactions;Incidence of myoclonus during induction of anesthesia;Incidence of choking during induction of anesthesia; | — |
Countries
China
Contacts
Public ContactWensheng Zhang
The Second Affiliated Hospital of Shandong First Medical University
Outcome results
None listed