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Impact of dynamic changes in serum growth differentiation factor-15 in patients with acute ST-segment elevation myocardial infarction on disease diagnosis and prognosis

Impact of dynamic changes in serum growth differentiation factor-15 in patients with acute ST-segment elevation myocardial infarction on disease diagnosis and prognosis

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400089639
Enrollment
Unknown
Registered
2024-09-12
Start date
2024-10-01
Completion date
Unknown
Last updated
2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute ST-segment elevation myocardial infarction

Interventions

group of STEMI:None
normal group:None

Sponsors

Affiliated Hospital of Qingdao University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. age =18 years; 2. meet the diagnostic criteria for STEMI in the 2023 ESC Guidelines for the Treatment of Acute Coronary Syndromes, with an onset of <12 h; 3. meet the indications for PCI and undergo PCI; 4. have informed consent from the patient or his/her legal representative.

Exclusion criteria

Exclusion criteria: 1. combined acute mechanical complications (aortic coarctation, coronary artery perforation, etc.), unprotected left main stem lesions, diffuse severe calcification and/or severe tortuosity and severe triple-branch lesions that are not suitable for PCI; 2. already undergone pharmacological thrombolysis; 3. pregnant or breastfeeding women; 4. other clinically significant respiratory, gastrointestinal, hematologic, infectious, immune, endocrine, neuropsychiatric, and oncologic diseases that may Patients who are not willing to receive treatment.

Design outcomes

Primary

MeasureTime frame
Growth differentiation factor-15;

Secondary

MeasureTime frame
N-terminal-B-type natriuretic peptide precursor;Troponin I;Hemoglobin;Leucocyte;Platelet;

Countries

China

Contacts

Public ContactXuezhi Zhang

Affiliated Hospital of Qingdao University

zxz_1204@163.com+86 178 5329 7218

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026