Acute myocardial infarction (AMI)
Conditions
Interventions
Vericiguat Group:Vericiguat + Standard AMI Medication + Emergency PCI
Standard Treatment Group:Standard AMI Medication + Emergency PCI
Sponsors
Shanghai Seventh People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. Age = 18 years; 2. All patients with acute myocardial infarction (AMI) are from our hospital and have undergone PCI treatment within 12 hours of onset; 3. Patients have signed informed consent and are able to participate in outpatient follow-up.
Exclusion criteria
Exclusion criteria: 1. Clinically diagnosed AMI patients with negative angiography results; 2. Patients who received thrombolytic therapy prior to emergency PCI; 3. Patients taking corticosteroids, immunosuppressants, or other drugs that affect blood inflammatory cytokine levels; 4. Severe hepatic or renal insufficiency; 5. Patients with psychiatric disorders; 6. Participation in other clinical trials within the past 3 months; 7. Pregnant or breastfeeding women, or those planning to become pregnant; 8. Patients deemed by the investigator to have poor compliance and unable to strictly follow the protocol; 9. Any other condition deemed unsuitable for the trial by the investigator, such as poor compliance or difficulty with follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Major Adverse Cardiovascular Events (MACE); | — |
Secondary
| Measure | Time frame |
|---|---|
| Left Ventricular Ejection Fraction (LVEF);Troponin;N-terminal pro b-type natriuretic peptide (NT-proBNP); | — |
Countries
China
Contacts
Public ContactZixuan Lu
Shanghai Seventh People's Hospital
Outcome results
None listed