Lumbar root neuralgia
Conditions
Interventions
Epidural PRP injection group:Inject 3ml of plasma rich in small platelets
Epidural steroid injection group:Inject 8mg dexamethasone palm ester injection (4mg/ml) and 1ml of 1% ropivacaine for a total of 3ml
Sponsors
Renji Hospital Shanghai Jiaotong University School of Medical
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Age = 18 years old and 6 weeks; 6.Pathological imaging results (magnetic resonance imaging) that are consistent with symptoms or signs (disc herniation, circular tear, or spinal stenosis); 7.Sign informed consent form.
Exclusion criteria
Exclusion criteria: 1.The patient requires surgical intervention; 2.Abnormal coagulation function (platelet count below 100 × 109/L, international normalized ratio [INR]>1.5); 3.Use anticoagulant and/or antiplatelet drugs (excluding aspirin); 4.History of epidural steroid injections in the past year; 5.Systemic infection; 6.History of lumbar spine surgery; 7.Allergy history: contrast agents, steroids, PRP, local anesthetics; 8.Pregnant/breastfeeding period; 9.Unable to tolerate epidural injection; 10.History of mental illness; 11.History of drug and alcohol abuse or drug abuse; 12.Patients with neurogenic claudication (pain in the lower legs, buttocks, and/or thighs caused by walking and/or standing upright for a long time); 13.Lower back pain is greater than leg pain; 14.Those who are unable to communicate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain score of waist/leg at 6 months after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain scores for waist/leg on postoperative day 1, month 1, and month 3;oswestry disability index;quality of life;Beck Depression Scale;EQ-5D Health Index;Overall changes in patient pain;Types of analgesic use; | — |
Countries
China
Contacts
Public ContactFan Yinghui
Renji Hospital Shanghai Jiaotong University School of Medical
Outcome results
None listed