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Depressive symptoms in patients with chronic schizophrenia: prevalence, clinical correlates, and associations with IL-1ß, IL-6, and CRP

Depressive symptoms in patients with chronic schizophrenia: prevalence, clinical correlates, and associations with IL-1ß, IL-6, and CRP

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400089584
Enrollment
Unknown
Registered
2024-09-11
Start date
2024-09-11
Completion date
Unknown
Last updated
2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

schizophrenia

Interventions

patient group:None
control group:None

Sponsors

Tianjin Beichen Anjin Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) Age= 18 years old; (2) Diagnosis of schizophrenia according to DSM-IV criteria; (3) Be in stable condition on antipsychotic drugs for at least half a year; (4) Chinese as mother tongue

Exclusion criteria

Exclusion criteria: (1) Currently pregnant or lactating; (2) diagnosis of other major mental disorders; (3) diagnosis of acute and chronic non-psychiatric diseases affecting the central nervous system; (4) Acute or chronic infection or treatment with anti-inflammatory or immunological agents in the past 3 months.

Design outcomes

Primary

MeasureTime frame
Beck Depression Inventory, BDI;Interleukin-1;C-reaction protein;Interleukin-6;

Secondary

MeasureTime frame
Positive and Negative Syndrome ,PANSS;

Countries

China

Contacts

Public ContactFuqiang Mao; Ming Gao

Department of Mental Health and Psychology, School of Basic Medical Sciences, Tianjin Medical University; Tianjin Beichen Anjin Hospital

maofq@tmu.edu.cn+86 137 0216 0048

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026