Stroke patients
Conditions
Interventions
Group A:Group A will receive 10 Hz high-frequency rTMS over the iM1 for 20 minutes, followed by 20 minutes of SRG, totaling 40 minutes. 1 time/day, 5 days/week
Group B:Group B will receive 5 minutes of 10 Hz high-frequency rTMS over iM1 followed by 5 minutes of SRG, repeated four times, totaling 40 minutes.1 time/day, 5 days/week
Group C:Group C will receive rTMS with the sham coil, with the same parameters as group A. All patients will receive routine rehabilitation training. In addition, patients will receive a 4-week neurol
Sponsors
The First Affiliated Hospital of Nanjing Medical University/Jiangsu Provincial People's Hospital
Eligibility
Sex/Gender
All
Age
40 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) ischemic stroke confirmed by CT and/or MRI meets the diagnostic criteria for cerebral infarction in the cerebrovascular disease; (2) primary or unilateral onset or previous onset without residual neurological dysfunction; (3) stable vital signs and clear consciousness; (4) the age ranges from 40 to 70 years; (5) the course of disease ranges from 1 week to 3 months; (6) Brunnstrom of hemiplegic upper limb and hand staging from I to III; (7) without cognitive dysfunction; and (8) the selected candidate or their relatives sign the informed consent form.
Exclusion criteria
Exclusion criteria: (1) epilepsy in the previous, a family history of epilepsy and taking medications that cause seizures; (2) severe deficits in cognition and communication that impede patient participation during evaluation and therapy; (3) posterior circulation infarction; (4) wearing a pacemaker, intracranial metal implants; (5) severe cervical spondylosis includes severe cervical stenosis and cervical spinal instability; (6) complete occlusion of the internal carotid artery; (7) direct injuries and skull defects in the stimulation area; and (8) women during pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fugl-Meyer Assessment – Upper Extremity; | — |
Secondary
| Measure | Time frame |
|---|---|
| Functional Test for the Hemiplegic Upper Extremity;Modified Ashworth Scale;ICF-Upper Extremity Entries; | — |
Countries
China
Contacts
Public ContactShen Ying
The First Affiliated Hospital of Nanjing Medical University/Jiangsu Provincial People's Hospital
Outcome results
None listed