Mild to moderate acne
Conditions
Interventions
test group:The experimental group received twice daily applications of La Roche-Posay Duo+M cream, once in the morning and once in the evening.
control group:The control group will receive twice-daily treatment with the comparator product.
Non-Acne Group:None
Sponsors
Southern Medical University Dermatology Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 35 Years
Inclusion criteria
Inclusion criteria: Experimental Group and Control Group: • Chinese males and females aged 18-35, in good general health • With mild to moderate/Grade 2-3 acne (IGA classification), meeting the indications for treatment with cosmeceuticals • With uneven skin tone and acne scars (PIE & PIH) • Signed informed consent by themselves/guardians • Good verbal and written communication and comprehension skills • Good compliance with the research protocol, willing to follow the research protocol by using the products provided during the entire study, refrain from using other medications and products, fill out the diary, and attend regular follow-up visits Group Without Acne Manifestations: • Chinese males and females aged 18-35, in good general health • Without acne manifestations/Grade 0 acne (IGA classification) • Signed informed consent by themselves/guardians • Good verbal and written communication and comprehension skills • Good compliance with the research protocol, willing to follow the research protocol throughout the study period
Exclusion criteria
Exclusion criteria: Main Exclusion Criteria: • Female participants who are pregnant, breastfeeding, or planning for pregnancy • Special types of acne: Acne conglobata, necrotizing acne, secondary acne, etc. • Systemic diseases with severe organ damage, malignant tumors, uncontrolled chronic diseases, acute infectious diseases, major surgeries or traumas, psychological or mental illnesses, or the need for local or systemic medications or treatments that may affect acne due to other medical conditions • Other skin diseases (such as rosacea, dermatitis, eczema, infections, tumors, etc.) on the study site or other skin conditions that may interfere with evaluation (such as birthmarks, scars, etc.) • Received topical medications or functional skincare products within the past 1 weeks • Received physical, chemical, or cosmetic surgical treatments within the past 2 weeks • History of oral/topical antibiotics and probiotic products in the past 2 weeks • Habits of scratching or squeezing acne lesions • History of allergy to the medications, products, or related ingredients provided in the study • Participating in other clinical studies simultaneously during the study period, refusing to sign the informed consent form, or poor compliance • Other situations deemed inappropriate for participation in the study by the investigators
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The absolute change in the count of inflammatory lesions;The absolute change in the count of non-inflammatory lesions; | — |
Secondary
| Measure | Time frame |
|---|---|
| Difference in Skin Biomarker Data;Skin physiological indicators; | — |
Countries
China
Contacts
Public Contactyang bin
Southern Medical University Dermatology Hospital
Outcome results
None listed