Motoric cognitive risk syndrome
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Inclusion criteria for the MCR group: (1)Age =60 years old; (2)Meeting the diagnostic criteria for MCR, including: 1)Absence of dementia, diagnosis was made according to community doctors combined with disease history, relevant examination and neuropsychological measures; 2)Subjective cognitive decline: Subjective Cognitive Decline Questionnaire (SCD-Q9) >3 was considered to be present; 3)Preserved basic activities of daily living: the score of ADL<16; 4) Slow gait speed: gait speed <100 cm/s was defined as the presence of slow gait speed; (3) Absence of self-reported visual or auditory impairment and normal reading comprehension techniques; (4) Elementary school level and above and able to perform writing tasks on their own, able to cooperate in completing questionnaires and physical assessments; (5) Able to make an informed consent. 2. Inclusion criteria for the normal control group: (1)Age =60 years old (2) Absence of self-reported visual or auditory impairment and normal reading comprehension techniques; (3) Elementary school level and above and able to perform writing tasks on their own, able to cooperate in completing questionnaires and physical assessments; (4) Able to make an informed consent.
Exclusion criteria
Exclusion criteria: MCR group and normal control group exclusion criteria: 1.Pre-existing or existing serious illnesses that affect cognitive functioning, such as physical illnesses, and severe mental illnesses (major depressive disorder, schizophrenia); 2.Inability to walk independently (using an assistive device such as a wheelchair); recent or anticipated medical interventions that may affect gait; 3.Those who are unable to perform writing tasks due to hand movement disorders; 4.Taking cognitive enhancers, drugs that impair cognitive function, or addictive substances within the past six months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Demographic sociological characteristics;Global cognitive function;Gait characteristics;Handwriting characteristics; | — |
Secondary
| Measure | Time frame |
|---|---|
| Memory function;Executive function;Attention;Visuo-spatial ability;Geriatric depression scale; | — |
Countries
China
Contacts
Huzhou University; Huzhou third people's Hospital