Essential hypertension
Conditions
Interventions
Control group:Oral hydrochlorothiazide
Experimental group:Oral hydrochlorothiazide + imidapril hydrochloride
Sponsors
Jiangyou Second People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) The subjects voluntarily agree to participate in the study and sign a written informed consent; (2) Age 18-75 years old, male or female; (3) Clinically diagnosed as hypertensive patients, meeting the diagnostic criteria for hypertension [systolic blood pressure = 140mmHg, and/or diastolic blood pressure =90 mmHg]; (4) Not taking antihypertensive drugs in the past 2 weeks or stopping the original antihypertensive drugs for more than 2 weeks.
Exclusion criteria
Exclusion criteria: (1) Those who have a history of allergy or contraindications to the investigational drugs and excipients; (2) A history of severe liver and kidney disease; (3) Patients with severe cerebrovascular disease within 6 months before enrollment; (4) Patients with respiratory cough (bronchitis, COPD, etc.) and throat discomfort; (5) Pregnant and lactating women; (6) Suspected or confirmed secondary hypertension; (7) The researcher thinks that it is not suitable to participate in this researcher.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Antihypertensive efficiency; | — |
Secondary
| Measure | Time frame |
|---|---|
| Dry cough; | — |
Countries
China
Contacts
Public ContactHong Le
Jiangyou Second People's Hospital
Outcome results
None listed