Esophageal cancer
Conditions
Interventions
Group A:Mckeown esophagectomy with 3D thoracoscopic and laparoscopic esophagectomy (right thoracic esophageal mobilization + upper abdominal gastric mobilization + neck anastomosis)
Group B:Mckeown esophagectomy with 2D thoracoscopic and laparoscopic esophagectomy (right thoracic esophageal mobilization + upper abdominal gastric mobilization + neck anastomosis)
Sponsors
Cancer Hospital, Chinese Academy of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) into the group signed a written informed consent before; 2) aged 18 to 80 years old; 3) pathology and imaging diagnosis; 4) cT1-2 nomo or cT1-3 nxm0 feasible radical resection of thoracic segment esophageal cancer patients; 5) ECOG score: 0 ~ 1; 6) the expected survival time is more than 6 months; 7) no major organ dysfunction: bone marrow reserve, liver and kidney function were evaluated to tolerate surgery; 8) subjects were willing to join in this study, good adherence, cooperate with the security and survival period of follow-up.
Exclusion criteria
Exclusion criteria: 1) the subjects had a history or concurrent history of other malignant tumors; 2) has a history of chest surgery; 3) need emergency surgery treatment of bleeding, perforation, obstruction, etc.; 4) severe cardiopulmonary dysfunction of liver and kidney researchers think that the person is not suitable for surgery; 5) patients with clinical symptoms of chest water, need therapeutic puncture and drainage; 6) subjects are participating in another clinical study or less than 1 month from the end of their previous clinical study; 7) subjects were known to have a psychiatric drug abuse, alcohol or illicit drugs; 8) The subjects were unable or did not agree to pay for the examination and treatment at their own expense; 9) researchers think that should be left out in this study, the researchers determine, for example, the subjects have other factors that may result in this study were forced to midway termination, such as, other serious disease (including mental illness) need to merge treatment, there are serious abnormal laboratory examination, accompanied by factors such as family or society, will affect the safety of the subjects, or information and the collection of the sample.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of postoperative week voice hoarse; | — |
Secondary
| Measure | Time frame |
|---|---|
| The number of lymph nodes dissected;The operation time;Intraoperative blood loss;R0 resection rate;The incidence of anastomotic leakage;The hospitalization time; | — |
Countries
China
Contacts
Public ContactYong Li
Cancer Hospital, Chinese Academy of Medical Sciences
Outcome results
None listed