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A prospective study on the association between minimal residual disease and prognosis in lung cancer

A prospective study on the association between minimal residual disease and prognosis in lung cancer

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400089554
Enrollment
Unknown
Registered
2024-09-10
Start date
2024-04-06
Completion date
Unknown
Last updated
2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung cancer

Interventions

Sponsors

Tongji Hospital Tongji Medical College of HUST
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1) Diagnosed with lung cancer; (2) In a good general condition; (3) Patients scheduled for surgical treatment; (4) Primary tumor WES testing has been performed or WES testing is planned; (5) Clearly understand and sign the informed consent form.

Exclusion criteria

Exclusion criteria: (1) Subject’s previous history of cancer; (2) Routine pathology is not non-small cell lung cancer; (3) Patients diagnosed with multiple primary tumors; (4) Patients receiving neoadjuvant therapy before surgery; (5) Postoperative pathology showed carcinoma in situ, minimally invasive adenocarcinoma, and stage IV lung cancer; (6) Patients who were lost to follow-up immediately after surgery; (7) Patients in whom somatic mutations were not detected in the primary tumor tissue; (8) Patients with contraindications to surgery; (9) Non-radical surgery; (10) Patients who are participating in other clinical trials; (11) Other situations that are not suitable for inclusion as assessed by the researcher.

Design outcomes

Primary

MeasureTime frame
Disease-free Survival, DFS;

Secondary

MeasureTime frame
Overall Survival, OS;Median time to relapse of patients with MRD detected by imaging in advance;

Countries

China

Contacts

Public ContactShengling Fu

Tongji Hospital Tongji Medical College of HUST

2008tj0517@hust.edu.cn+86 137 2016 5003

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026