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The effect of different concentrations of brachial plexus block with liposomal bupivacaine on postoperative pain in patients undergoing arthroscopic shoulder surgery: A Noninferiority Trial

The effect of different concentrations of brachial plexus block with liposomal bupivacaine on postoperative pain in patients undergoing arthroscopic shoulder surgery: A Noninferiority Trial

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400089536
Enrollment
Unknown
Registered
2024-09-10
Start date
2024-08-12
Completion date
Unknown
Last updated
2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative pain after arthroscopic surgery

Interventions

Experimental group:Liposomal bupivacaine 15ml
Control group:Liposomal bupivacaine 20ml

Sponsors

Zhuji People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Age=18 years old, ASA grade I-III, BMI18-30kg/m2 2. Preoperative magnetic resonance imaging confirmation of ligament tear > 1cm

Exclusion criteria

Exclusion criteria: 1. Refused to participate in the study 2.allergy to local or general anesthetics, or contraindication to brachial plexus block contraindication 3. had chronic pain or a long history of opioid use 4. had severe cardiovascular or cerebrovascular diseases 5. had severe hepatic or renal insufficiency 6. had an inability to understand pain scores or PCIA, or failure of brachial plexus block

Design outcomes

Primary

MeasureTime frame
48 hour postoperative resting NRS score;

Secondary

MeasureTime frame
The time of first analgesic request;Postoperative 1-3days NRS score ;The number of PCIA compressions;Motor block time;Postoperative complications;Postoperative sleep quality;Postoperative remedial analgesia;

Countries

China

Contacts

Public ContactXing Rong

Zhuji People's Hospital

1477952924@qq.com+86 138 6752 8192

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026