Endometriosis
Conditions
Interventions
Experimental group: Patients with infertility and endometriosis.:Iodine Contrast Imaging
Positive control group: Endometriosis patients who did not undergo oil-based contrast hysterosalpingography (HSG).:No intervention
Negative control group: Patients undergoing laparoscopic surgery for non-endometriosis-related conditions such as uterine fibroids or ovarian cysts.:No intervention
Sponsors
The First Affiliated Hospital of Guangxi Medical University
Eligibility
Sex/Gender
Female
Age
18 Years to 39 Years
Inclusion criteria
Inclusion criteria: The inclusion criteria were as follows: 1) Female patients with endometriosis aged between 18 and 39 years old; 2) Having a natural menstrual cycle; 3) Having undergone HSG.
Exclusion criteria
Exclusion criteria: The exclusion criteria were: 1) Female participants with uncontrolled endocrine disorders known to diminish natural pregnancy chances (e.g., the acute phase of systemic lupus erythematosus); 2) Total motile sperm count after sperm wash of less than 3 million sperm per milliliter in the male partner (or a total motile sperm count of <1 million sperm per milliliter when an analysis after sperm wash was not performed); 3) Participants with incomplete data.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Glycoprotein 130(pg130); | — |
Secondary
| Measure | Time frame |
|---|---|
| Cell Counting Kit-8(CCK8);SA-ß-gal staining;TNF-alpha; Reactive Oxygen Species(ROS);Tumor Protein 53(p53);Cyclin-Dependent Kinase Inhibitor 1(p21);Cyclin-Dependent Kinase Inhibitor 2A(p16);Lamin B;Prolactin(PRL);Insulin-like Growth Factor Binding Protein 1(IGFBP1);Interleukin-18(IL-18);Interleukin-6(IL-6); | — |
Countries
China
Contacts
Public ContactAiping Qin
The First Affiliated Hospital of Guangxi Medical University
Outcome results
None listed