Calcium oxalate stones
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Primary diagnosis: calcium oxalate stones; (2) Age: 18-60 years; (3) Have had more than 2 stone recurrences in the past 3-5 years and admitted to hospital; (4) Informed about the study and signed an informed consent form.
Exclusion criteria
Exclusion criteria: (1) Acute renal failure or glomerular filtration rate (GFR) <30 mL/min/1.73m^2 at screening; (2) Patients with recurrent uric acid stones; (3) Obstructive uropathy, renal failure, renal tubular acidosis, chronic uremia, and medullary sponge kidney; (4) Patients with severe digestive disorders (e.g., acute peptic ulcer, chronic ulcerative colitis, restrictive enteritis, intestinal obstruction), malignancy, cardiovascular disease, active autoimmune disease, hypercalcaemia or hypothyroidism; (5) Hypertension and diabetes mellitus that cannot be effectively controlled clinically. (6) Failure to sign the informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total 24h urinary oxalate excretion; | — |
Countries
China
Contacts
Tsinghua University Affiliated Beijing Tsinghua Changgung Hospital