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Clinical study on adverse reactions of midapril hydrochloride in treating essential hypertension induced dry cough

Clinical study on adverse reactions of midapril hydrochloride in treating essential hypertension induced dry cough

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400089524
Enrollment
Unknown
Registered
2024-09-10
Start date
2024-08-19
Completion date
Unknown
Last updated
2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Essential hypertension

Interventions

Imidapril hydrochloride group:Oral administration of midapril hydrochloride 5-10mg

Sponsors

The Third Hospital of Hebei Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: (1) The subjects voluntarily agree to participate in the study and sign a written informed consent; (2) Age 18-75 years old, male or female; (3) Clinically diagnosed as hypertensive patients, meeting the diagnostic criteria for hypertension [systolic blood pressure = 140mmHg, and/or diastolic blood pressure =90 mmHg]; (4) Not taking antihypertensive drugs in the past 2 weeks or stopping the original antihypertensive drugs for more than 2 weeks.

Exclusion criteria

Exclusion criteria: (1) Those who have a history of allergy or contraindications to the investigational drugs and excipients; (2) A history of severe liver and kidney disease; (3) Patients with severe cerebrovascular disease within 6 months before enrollment; (4) Patients with respiratory cough (bronchitis, COPD, etc.) and throat discomfort; (5) Pregnant and lactating women; (6) Suspected or confirmed secondary hypertension; (7) The researcher thinks that it is not suitable to participate in this researcher

Design outcomes

Primary

MeasureTime frame
dry cough;

Secondary

MeasureTime frame
Blood pressure;Heart rate;

Countries

China

Contacts

Public ContactGeng Xiaoyong

The Third Hospital of Hebei Medical University

754746206@qq.com+86 137 0830 2754

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026