Effect of TPVB and ESPB on the perioperative period in patients undergoing laparoscopic radical surgery for colorectal cancer

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400089500

Enrollment

Unknown

Registered

2024-09-10

Start date

2024-09-16

Completion date

Unknown

Last updated

2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal cancer

Interventions

Group T:Paravertebral nerve block in the T10 plane bilaterally (0.375% ropivacaine each side)

Group E:Bilateral T10 planar block in the plane of the erector spine muscle (0.375% ropivacaine each side)

Group C:general anaesthesia only

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Elective radical laparoscopic colorectal cancer surgery under general anaesthesia; age: 18 -80years; body mass index (BMI): 18-32 kg/m2; ASA: class II-III.

Exclusion criteria

Exclusion criteria: Those with contraindications to regional blockade and related medications; those with spinal and thoracic deformities; those with severe respiratory and circulatory dysfunction and abnormalities of liver and kidney function; those with chronic pain and long-term opioid use (>4 weeks); pregnant or breastfeeding patients; those with psychiatric disorders; and those who are unable to cooperate.

Design outcomes

Primary

Measure	Time frame
15-item quality of recovery;	—

Secondary

Measure	Time frame
Numeric rating scale;Opioid dosage;Mini-mental state examination;C-reactive protein;Tumor necrosis factor-a;Leeds Assessment of Neuropathic Symptoms and Signs(self-complete);	—

Countries

China

Contacts

Public ContactHu Jie

Luoyang Central Hospital

13721624858@163.com+86 137 2162 4858

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026