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Clinical study of topical NSAIDs for pain relief in osteoarthritis: a randomized controlled trial

Clinical study of topical NSAIDs for pain relief in osteoarthritis: a randomized controlled trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400089493
Enrollment
Unknown
Registered
2024-09-10
Start date
2024-10-08
Completion date
Unknown
Last updated
2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

osteoarthritis

Interventions

Research group:Treatment with Ketoprofen Cataplasms,twice a day
Control group:Treatment with Flurbiprofen Cataplasms,twice a day

Sponsors

Qingdao Traditional Chinese Medicine Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: (1) The subjects voluntarily agree to participate in the study and sign a written informed consent; (2) Age 18-75 years old, male or female; (3) Clinically diagnosed patients with osteoarthritis; (4) No previous bleeding, asthma, severe cardiac, liver and renal insufficiency, non-steroidal drug allergy history; (5) The study/control drugs used by the patient were included in the drug list specified in this study.

Exclusion criteria

Exclusion criteria: (1) previous treatment that may affect the efficacy; (2) Patients with open wounds, scars or ulcers in the gel paste application area; (3) fracture, dislocation, etc.; Accompanied by tumors, cardiovascular and cerebrovascular diseases, blood diseases and other serious primary diseases, or accompanied by mental disorders and communication disorders can not determine the efficacy. Radiating pain or dysfunction caused by other diseases (visceral organ diseases, cardiovascular and cerebrovascular diseases); (4) Pregnant and lactating women or women of childbearing age who are trying to conceive; (5) Other situations in which the researcher considers it inappropriate to participate in this experiment

Design outcomes

Primary

MeasureTime frame
Overall response rate;

Secondary

MeasureTime frame
VAS score;WOMAC score;Lysholm Score;

Countries

China

Contacts

Public ContactHou Zengtao

Qingdao Traditional Chinese Medicine Hospital

houzengtao@163.com+86 136 7888 2998

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026