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Comparison of cyclopofol and propofol in bronchoscopic non-tracheal intubation general anesthesia

Comparison of cyclopofol and propofol in bronchoscopic non-tracheal intubation general anesthesia

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400089460
Enrollment
Unknown
Registered
2024-09-09
Start date
2024-05-01
Completion date
Unknown
Last updated
2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bronchoscopy is required for diagnosis and treatment of related diseases

Interventions

Low dose cyclopofol group:Anesthesia was induced by 0.3mg/kg cyclopofol combined with 0.8ug/kg remifentanil
Propofol group:Anesthesia was induced by 1.2mg/kg propofol combined with 0.8ug/kg remifentanil
High dose cyclopofol group:Anesthesia was induced by 0.4mg/kg cyclopofol combined with 0.8ug/kg remifentanil

Sponsors

Weifang Second People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: A certain number of ASA? - ? patients, aged 18-65 years, and BMI18-30, who received bronchoscopy were selected, no history of major organ diseases such as heart, lung, liver, kidney, etc, no history of anesthesia drug allergy, and there are no abnormalities in preoperative blood routine and electrocardiogram.

Exclusion criteria

Exclusion criteria: (1) People allergic to propofol or its excipients; (2) People who are allergic to soy or peanuts; (3) Use of analgesics or anti-anxiety drugs within 1 h before surgery; (4) Usually long-term use of non-steroidal anti-inflammatory drugs or opioids treatment; (5) Patients suffering from neurological or mental disorders, language communication disorders.

Design outcomes

Primary

MeasureTime frame
mean arterial pressure;Respiratory rate;Partial pressure of end-expiratory carbon dioxide;Heart rate;Incidence of intraoperative adverse reactions;

Countries

China

Contacts

Public ContactHua Yan

Weifang Second People's Hospital

76094250@qq.com+86 135 0647 1080

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026