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Comparison of therapeutic effects between posterior percutaneous full-endoscopic cervical discectomy and collagenase chemolysis in the treatment of cervical spondylotic radiculopathy

Comparison of therapeutic effects between posterior percutaneous full-endoscopic cervical discectomy and collagenase chemolysis in the treatment of cervical spondylotic radiculopathy

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400089451
Enrollment
Unknown
Registered
2024-09-09
Start date
2023-06-02
Completion date
Unknown
Last updated
2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cervical spondylotic radiculopathy

Interventions

Endoscopy group:posterior percutaneous full-endoscopic cervical discectomy
Collagenase group:collagenase chemonucleolysis

Sponsors

The Frist Affiliated Hospital of Anhui Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1.Symptoms of typical unilateral nerve root compression; 2.Age = 18 years old, = 75 years old; 3.Those who have undergone conservative treatment for 3 months or more but have not achieved satisfactory results ; 4.The preoperative cervical spine imaging showed protrusion leaning towards the affected side and compressing the nerves, which was consistent with the patient's clinical symptoms and signs; 5.VAS score = 5 points, out of 10 points; 6.Volunteer to participate in this study and sign an informed consent form.

Exclusion criteria

Exclusion criteria: 1.Patients with mixed cervical spondylosis also have other diseases that can induce upper limb pain, such as scapulohumeral periarthritis, carpal tunnel syndrome, and thoracic outlet syndrome; 2.Complications include cervical spine trauma, severe spinal deformities, and cervical infection. 3.Patients with severe cardiopulmonary insufficiency who cannot tolerate surgery

Design outcomes

Primary

MeasureTime frame
visual analogue scale;MacNab efficacy evaluation criteria;

Secondary

MeasureTime frame
Japanese Orthopaedic Associationscores, JOA;Neck Disability Index , NDI;Disc height;

Countries

China

Contacts

Public ContactWang Likui

The Frist Affiliated Hospital of Anhui Medical University

gyy19810755306@163.com+86 137 0569 0702

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026