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A prospective, split-face study of microneedle radiofrequency versus fractional CO2 laser in the treatment of facial atrophic acne scars

Comparison of the efficacy and safety of invasive microneedle radiofrequency and CO2 fractional laser in the treatment of facial atrophic acne scarring

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400089446
Enrollment
Unknown
Registered
2024-09-09
Start date
2021-03-05
Completion date
Unknown
Last updated
2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

atrophic acne scar

Interventions

FCO2:another half of the face treated with fractional CO2 laser
MRF:one half of the face treated with invasive MRF

Sponsors

ZhongDa Hospital, Southeast University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Patients with symmetrical atrophic acne scarring on the face, aged = 18 years and < 75 years, who understand and voluntarily sign the informed consent, and are able to complete treatment and follow-up as required.

Exclusion criteria

Exclusion criteria: History of keloid scarring, history of oral retinoic acid medication within 6 months prior to treatment, history of facial injections and fillers, laser or radiofrequency treatments, history of photoallergy and photosensitizing medications, allergy to lidocaine, coagulation abnormalities, history of oral glucocorticosteroids and immunosuppressive drugs within 3 months prior to treatment, patients with malignant neoplasms, pregnant and lactating women, and active herpes simplex on the face.

Design outcomes

Primary

MeasureTime frame
ECCA;ultrasonographic changes;

Secondary

MeasureTime frame
patient self-rated improvement;adverse effects;

Countries

CHINA

Contacts

Public ContactSu Qianya

Zhongda Hospital, Southeast University

suqianya@163.com+86 180 5100 7932

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026