Tic disorder
Conditions
Interventions
Probiotics assisted treatment group:Take bifidobacterium breve ProSci-106 and drug (receive standard treatment), once a day, one bag at a time, for a total of 3 months
Placebo group:Take a placebo and drug (receiving standard treatment) once a day, one bag at a time, for 3 months
Sponsors
Inner Mongolia Autonomous Region People's Hospital
Eligibility
Sex/Gender
All
Age
6 Years to 14 Years
Inclusion criteria
Inclusion criteria: 1. The legal guardian knows and agrees to participate in the study voluntarily and signs the informed consent; 2. Age 6-14 years old, no gender restrictions; 3. Refer to the American Psychiatric Association's Diagnostic and Statistical Manual of mental disorders (DSM-5) criteria for diagnosis of tic disorder.
Exclusion criteria
Exclusion criteria: 1. Those who do not meet the above inclusion criteria; 2. People who are allergic to probiotics or its ingredients; 3. Patients with primary diseases such as digestive system and immune system, or suffering from other serious diseases; 4. Diet and exercise therapy as recommended by a doctor; 5. Have used antibiotics, probiotics or Biostime within the last month; 6. Exclude involuntary movements that can be explained by other diseases, such as rheumatic chorea, Huntington's disease, hepatolenticular degeneration, hyperactivity disorder, muscle spasms, hysterical attacks, and other extrapyramidal diseases; 7. Participated in other clinical trials within the past month; 8. Subjects who are unwilling to provide personal information and do not wish to be included in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Basic information questionnaire;Yale Global Tic Severity Scale-Total Tic Score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Yale Global Tic Severity Scale-Total Score;Gastrointestinal Symptoms Rating Scales; | — |
Countries
China
Contacts
Public ContactYang An
Inner Mongolia Autonomous Region People's Hospital
Outcome results
None listed