Helicobacter pylori infection
Conditions
Interventions
intervention group:Tegoprazan 50mg twice a day and amoxicillin 1.0g three times a day for 10 days
control group:Rabeprazole 20mg twice a day, amoxicillin 1.0g twice a day, Furazolidone 0.1g twice a day, colloidal bismuth pectin 200mg twice a day for 10 days
Sponsors
Chengdu Xinhua Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Age range from 18 to 75 years old, both male and female are welcome; 2. Clearly diagnose newly diagnosed patients with HP; 3. 13 C-urea breath test (13 C-UBT) or 14 C-urea breath test (14 C-UBT) positive; 4. The rapid urease test of gastroscopy biopsy was positive; 5.Confirmed by histopathological examination; 6.Monoclonal antibody fecal antigen test positive.
Exclusion criteria
Exclusion criteria: 1. Aged 75 years; 2. Pregnancy, lactation, serious concomitant diseases, malignant tumors, allergic study drugs, severe ulcer bleeding or perforation, history of upper gastrointestinal surgery, previous treatment with H. pylori, PPI or antibiotics within 4 weeks. 3. All patients underwent their first HP eradication treatment, and those who failed the first treatment and required remedial treatment, as well as those allergic to amoxicillin, were not included in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Helicobacter pylori eradication rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| adverse reaction;adherence; | — |
Countries
China
Contacts
Public ContactHuang Yuanlong
Chengdu Xinhua Hospital
Outcome results
None listed