Skip to content

A Single-center Two-way Cohort Study on the Effectiveness of Different Radiofrequency Ablation Strategies for Persistent Atrial Fibrillation

A Single-center Two-way Cohort Study on the Effectiveness of Different Radiofrequency Ablation Strategies for Persistent Atrial Fibrillation

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400089408
Enrollment
Unknown
Registered
2024-09-09
Start date
2024-10-14
Completion date
Unknown
Last updated
2025-09-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Persistent atrial fibrillation

Interventions

EPS negative group:None
EPS positive group:None

Sponsors

Sun Yat sen Memorial Hospital of Sun Yat sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) Aged 18-80 years old; (2) Confirmed persistent atrial fibrillation by Holter electrocardiogram; (3) Willing to undergo radiofrequency ablation treatment for the first time and have signed the surgical consent form.

Exclusion criteria

Exclusion criteria: (1) Patients with paroxysmal atrial fibrillation; (2) Severe organic heart disease (severe mitral regurgitation, dilated cardiomyopathy, hypertrophic cardiomyopathy, and other severe valvular diseases); (3) Patients with congenital heart disease or patent foramen ovale, who have undergone closure or surgical repair; (4) Post-artificial valve implantation; (5) With contraindications to systemic anticoagulation; (6) History of stroke due to any reason within the last 3 months; (7) History of bleeding within the last 30 days or a previous high risk of bleeding; (8) Platelet count 3 times the upper limit of normal (ULN); (13) Life expectancy less than 1 year; (14) Previous implantation of any type of pacemaker or left atrial appendage closure device; (15) Acute myocardial infarction or percutaneous coronary intervention (PCI) within the last 3 months, or coronary artery bypass grafting (CABG) within the last 6 months; (16) Previous catheter ablation for arrhythmias (including atrial fibrillation); (17) Left atrial anteroposterior diameter >= 50mm measured by parasternal long-axis view; (18) Left ventricular ejection fraction < 40% or in a state of decompensated heart failure.

Design outcomes

Secondary

MeasureTime frame
Total procedural time;Fluoroscopy time;Total radiofrequency ablation time;

Primary

MeasureTime frame
Sinus rhythm maintenance rate in 1 year;

Countries

China

Contacts

Public ContactChen Yuyang

Sun Yat sen Memorial Hospital of Sun Yat sen University

cyy6381@163.com+86 158 2028 4142

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026