Polycystic ovarian syndrome
Conditions
Interventions
Control group:On the 5th day of the menstrual cycle, Diane-35 was taken orally once a day for 21 consecutive days. Continuous medication for 3 menstrual cycles.
Treatment group:On the basis of the control group, Xiaoangtiaojing Decoction of traditional Chinese medicine granules was added on the 5th day of menstrual cycle, one dose a day, divided into morning
Sponsors
Henan Province Hospital of TCM
Eligibility
Sex/Gender
Female
Age
21 Years to 35 Years
Inclusion criteria
Inclusion criteria: 1. In line with the diagnostic criteria of PCOS Western medicine and the standard of TCM syndrome differentiation; 2. 21 = age = 35 years old and have fertility requirements; 3. Color ultrasound thickness < 7mm during embryo implantation window period; 4. Uterus, ovary and fallopian tube examination are normal, no other diseases affecting conception and pregnancy; 5. Did not receive hormone therapy for 3 months prior to treatment; 6.Those who voluntarily participate in the experiment and sign the informed consent;
Exclusion criteria
Exclusion criteria: 1.There were clinical manifestations of hyperandrogenemia caused by other diseases; 2.There were other causes of abnormal ovulation disease; 3.Patients who have taken drugs such as contraceptives within the last 3 months that may affect the effect and outcome of this study, or who are allergic to the drugs used in this study; 4.Patients with severe primary diseases of cardiovascular and blood system, severe liver and kidney dysfunction and mental illness; 5.Those who failed to follow the doctor 's advice. This study does not comply with, do not cooperate, easy to produce lost to follow-up ; 6.Accompanied by other physiological or pathological conditions that may affect the observation and judgment of the effect indicator; If the samples were receiving drug therapy at the time of selection and met the inclusion criteria after the washout period, they were not considered excluded cases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Endometrial Thickness;Anti-Müllerian Hormone;Insulin -like Growth Factor BindingProtein – 1;Uterine artery pulsatility index;Uterine artery resistance index;Fasting insulin level;Insulin resistance index;miR-155;miR-194; | — |
Secondary
| Measure | Time frame |
|---|---|
| Chinese medicine syndrome scores;Fasting blood glucose;Testosterone;Luteinizing Hormone;Follicle-stimulating hormone;Lnterleukin-6; | — |
Countries
China
Contacts
Public ContactYanyan Zhou
Henan Province Hospital of TCM
Outcome results
None listed