A multicenter, randomised controlled trials on the effect of microbiome intervention on assisted reproductive technology outcomes in overweight/obese patients

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400089397

Enrollment

Unknown

Registered

2024-09-08

Start date

2024-09-20

Completion date

Unknown

Last updated

2024-09-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

overweight, infertility

Interventions

Intervention group:Microbiome intervention

Control group:N/A

Eligibility

Sex/Gender

Female

Age

20 Years to 40 Years

Inclusion criteria

Inclusion criteria: (1)Aged 20-42 years; (2)BMI: =25kg/m2; (3)AMH=1.2ng/ml; (4) Signed informed consent.

Exclusion criteria

Exclusion criteria: (1)Receiving weight loss products or bariatric surgery treatment; (2)No clinical pregnancy has been obtained after =3 embryo transfer cycle cycles; (3)Patients with uterine abnormalities diagnosed by ultrasound or severe uterine adhesions diagnosed by hysteroscopy; (4)Patients with secondary obesity (e.g. hyperthyroidism, hypothyroidism); (5)Combined with other diseases that are not suitable for pregnancy in the short term

Design outcomes

Primary

Measure	Time frame
Live birth rate;	—

Secondary

Measure	Time frame
Implantation rate;Abortion rate;	—

Countries

China

Contacts

Public ContactYimin Zhu

Women's Hospital, School of Medicine, Zhejiang University

zhuyim@zju.edu.cn+86 136 0581 2866

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026