respiratory disease
Conditions
Interventions
Remimazolam group:remizazolam
Propofol group:propofol
Sponsors
The Fourth Affiliated Hospital of Soochow University(Suzhou Dushu Lake Hospital)
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.Patients scheduled to undergo a diagnostic and(or) therapeutic bronchoscopy with venous anethesia; 2.Aged 18 ~70 years,regardless of gender; 3.American society of Anesthesiologists (ASA) physical status ? ~ ?; 4.Body mass index (BMI) 18~30 kg/m2; 5.Understanding and voluntary participation in the study, with informed consent signed by an individual or family member
Exclusion criteria
Exclusion criteria: 1.Peripheral oxygen saturation(SpO2) baseline value =95%; 2.The procedure was expected to take longer than one hour; 3.Severe cardiovascular or respiratory diseases; 4.Renal or liver dysfunction; 5.Neurocognitive or psychiatric disorders,traumatic brain injury or epilepsy; 6.Alcoholism, preoperative use of sedatives or analgesics;6.Hypersensitivity to the medications in this study; 7.Hypersensitivity to the medications in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Composite of desaturation and hypotension; | — |
Secondary
| Measure | Time frame |
|---|---|
| Desaturation;Hypotension;Dizziness;Unconscious body movements;Injection pain;Fatigue score;Patient satisfaction;Endoscopist satisfaction;Induction time;Recovery time;Tidal impedance variation,TIV;Center of ventilation ,COV;Global inhomogeneity index,GI index; | — |
Countries
China
Contacts
Public ContactZhang Lan
The Fourth Affiliated Hospital of Soochow University(Suzhou Dushu Lake Hospital)
Outcome results
None listed