deep infiltrating endometriosis
Conditions
Interventions
Pregnancy group:Pregnant patients after DIE surgery
Non-pregnancy group:Non-pregnant patients after DIE surgery
Prospective research group:Prospective inclusion and follow-up of postoperative pregnancy outcomes in patients undergoing DIE surgery
Sponsors
Obstetrics and Gynecology Hospital of Fudan University
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1.1 Inclusion criteria for retrospective studies: 1) From January 2009 to January 2022, DIE patients underwent surgical treatment with pathological diagnosis of DIE in the Obstetrics and Gynecology Hospital of Fudan University, ; 2) Complete medical history records (basic information, surgical and medical records) and pathological data; 3) Preoperative specialized examination records: vagino-recto-abdominal examination; Complete imaging examinations such as B-ultrasound and MRI before surgery, and have complete imaging data; 4) Telephone follow-up successful, recording pregnancy outcomes. 1.2 Inclusion criteria for prospective studies: 1) Prospective collection of patients with clinical diagnosis of DIE combined with infertility; 2) Age range: 18-45 years old; 3) Intending to be hospitalized for DIE surgical treatment, with complete medical history information available; 5) Intraoperative histopathological specimens can be obtained, and postoperative pathology confirms the DIE subtype; 6) Accepting regular long-term follow-up 7) Sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1) Refuse long-term follow-up; 2) Merging gynecological malignant tumors or other gynecological hormone dependent diseases; 3) Incomplete medical history data, inability to cooperate with gynecological specialist examinations, or lack of imaging data, serum biomarker reports, etc; 4) Postoperative pathological diagnosis didn't indicate endometriosis. 5) Male with abnormal semen
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| pregnant rate;Safety index; | — |
Secondary
| Measure | Time frame |
|---|---|
| recurrence rate;surgery complications;Health economics;EHP-30;FSFI;Sex hormone levels; | — |
Countries
China
Contacts
Public ContactZhang Ning
Obstetrics and Gynecology Hospital of Fudan University
Outcome results
None listed