pre-oxygenation combined with apneic oxygenation
Conditions
Interventions
Mask pre-oxygenation group:Use a mask at 10 L/min for pre-oxygenation, and do not give oxygen during apnea.
High flow nasal cannula pre-oxygenation group:Use a high-flow nasal cannula at 30 L/min for pre-oxygenation, and do not give oxygen during apnea.
High-flow nasal cannula pre-oxygenation combined with apnea oxygenation group:Use high-flow nasal cannula 30 L/min for pre-oxygenation
use high-flow nasal cannula 60 L/min to provide oxygen during apnea.
Anesthesia-specific nasal mask pre-oxygenation group:Use an anesthesia-specific nasal mask 10L/min for pre-oxygenation, and no oxygen is given during apnea.
Anesthesia-specific nasal mask pre-oxygenation combined with apnea oxygenation group:Use an anesthesia-specific nasal mask Perform pre-oxygenation at 10 L/min, and use a special nasal mask for anesthe
Sponsors
Gansu Provincial People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Patients aged 18-65 years 2.ASA grade I-II,BMI>28kg/m2 3.Elective surgery patients undergoing general anesthesia 4.Patients voluntarily participate in this study and sign the informed consent form
Exclusion criteria
Exclusion criteria: 1) Chronic respiratory diseases; Uncontrolled hypertension; congestive heart failure; 2) Nasal congestion, nasal lesions 3) Pregnant women, anemia 4) Patients at high risk of aspiration (e.g. intestinal obstruction, etc.) 5) Patients who are unable to tolerate hypercapnia (pulmonary hypertension, neurological space-occupying lesions)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| safe apnea time;Intraoperative adverse events (hypotension, arrhythmia, laryngospasm);Postoperative adverse events (nasal dryness and pain, pharynx dryness and pain, tinnitus, flatulence);End-tidal CO2 partial pressure;Hemodynamics:mean arterial pressure (MAP);partial pressure of arterial oxygen,arterial carbon dioxide partial pressure,PH; | — |
Secondary
| Measure | Time frame |
|---|---|
| Oxygen concentration under the sound gate;Gastric antrum ultrasound cross-sectional area.; | — |
Countries
China
Contacts
Public ContactWenjun YAN
Gansu Provincial People's Hospital
Outcome results
None listed