Helicobacter pylori infection
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Determine Helicobacter pylori infection by C13 or C14 breath test or rapid urease test; 2. Vonolasone plus high-dose amoxicillin or Vonolasone plus metronidazole+amoxicillin+bismuth quadruple therapy; 3. The age is between 18 and 75; 4. I have not participated in other research projects at present; 5. Agree to participate in this research topic and sign the informed consent form; 6. Penicillin skin test is negative;
Exclusion criteria
Exclusion criteria: 1. Use antibiotics, PPI, H2 receptor antagonists, bismuth and other drugs in the last month; 2. Lactating or pregnant women; 3. Have serious diseases such as heart, lung, liver and kidney; 4. Suffering from digestive tract tumors and malignant tumors in other parts or chronic diseases in other systems; 5. Have an allergic history to any of the drugs in the scheme (voronin, amoxicillin, metronidazole, bismuth potassium citrate). 6. The above two schemes were not adopted to eradicate Hp.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Eradication rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Medicine compliance; Adverse reaction rate; | — |
Countries
China
Contacts
Shanghai General Hospital