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Preliminary application and evaluation of exhaled air condensate biomarkers in CARAS

Preliminary application and evaluation of exhaled air condensate biomarkers in CARAS

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400089351
Enrollment
Unknown
Registered
2024-09-06
Start date
2023-04-19
Completion date
Unknown
Last updated
2024-09-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

combined allergic rhinitis and asthma syndrome, CARAS

Interventions

CARAS group:None
Healthy People Group:None

Sponsors

The First Affiliated Hospital of Henan University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) Patients with AR, BA and CARAS who meet the Western medical diagnostic criteria; (2) Chinese medical evidence consistent with lung qi deficiency evidence, phlegm-heat congestion of the lung evidence or wind-heat offending the lung evidence; (3) Age 18 to 80 years; (4) Voluntarily accepted the study and signed an informed consent form; (5) Not participated in other clinical studies within 1 month prior to enrollment.

Exclusion criteria

Exclusion criteria: (1) Patients with combined vasomotor rhinitis and eosinophilic non-allergic rhinitis, other non-allergic rhinitis diseases that can cause symptoms such as nasal congestion and runny nose; (2) Patients who are participating in other drug trials; (3) Patients with a combination of other serious systemic diseases; (4) Pregnant or lactating women; (5) Patients with confusion, disorders of consciousness, dementia, and various psychiatric disorders.

Design outcomes

Primary

MeasureTime frame
Interleukin-2,4,5,13 (IL-2,4,5,13);Interferon-?, IFN-?;Tumor Necrosis Factor-ß, TNF-ß;Eosinophil Cationic Protein, ECP;Forced expiratory volume in one second / forced vital capacity, FEV1/FVC;

Secondary

MeasureTime frame
Fractional exhaled nitric oxide, FeNO;Forced vital capacity, FVC;Forced expiratory volume in one second, FEV1;Percentage of forced expiratory volume in one second to predicted value, FEV1% pred;

Countries

China

Contacts

Public ContactYanmin Shi, Yang Xie

The First Affiliated Hospital of Henan University of Chinese Medicine

shiyanmin0525@sina.cn+86 188 3890 6711

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026